TABLE 2

Molecular ions (MH+) and MS2 fragmentation pathways of aripiprazole metabolites in NADPH-supplemented human liver microsomes

Metabolite
Proposed Structure
MH+ (m/z)
MS2
M12 Embedded Image 247 204, 168 (100%), 133
M13 Embedded Image 480 462, 301 (100%), 259
M14 Embedded Image 231 188 (100%), 152, 117
M15 Embedded Image 303 231 (100%), 188, 152, 117
M16 Embedded Image 464 301 (100%), 259, 218, 176
M17 Embedded Image 464 285 (100%), 234, 216
M18 Embedded Image 462 285 (100%), 232
M19
Embedded Image
446
285 (100%), 243, 216