Parameter | Rat 1 | Rat 2 | Rat 3 | Mean | S.D. |
---|---|---|---|---|---|
AUC, nM ยท h | 10,029 | 26,060 | 15,442 | 17,177 | 8155 |
nmol Dosed | 6565 | 5878 | 5290 | 5911 | 638 |
nmol Excreted | 652 | 895 | 680 | 742 | 133 |
Rat weight, kg | 0.20 | 0.21 | 0.19 | 0.20 | 0.01 |
Clsys, l/h/kg | 3.3 | 1.1 | 1.9 | 2.07 | 1.11 |
Clsi, l/h/kg | 0.3 | 0.2 | 0.2 | 0.24 | 0.08 |