Parameter | N | % |
---|---|---|
VDss | ||
Compounds less than 0.1 l/kg | 17 | 2.5 |
Compounds between 0.1 and 0.7 l/kg | 260 | 39 |
Compounds between 0.7 and 2 l/kg | 197 | 29 |
Compounds between 2 and 10 l/kg | 143 | 21 |
Compounds 10 l/kg or greater | 53 | 7.9 |
CL | ||
Compounds less than 1 ml/min/kg | 104 | 16 |
Compounds between 1 and 5 ml/min/kg | 262 | 39 |
Compounds between 5 and 15 ml/min/kg | 200 | 30 |
Compounds between 15 and 21 ml/min/kg | 48 | 7.2 |
Compounds greater than 21 ml/min/kg | 56 | 8.4 |
Half-life (t1/2) | ||
Compounds less than 1 h | 64 | 10 |
Compounds between 1 and 4 h | 266 | 40 |
Compounds between 4 and 12 h | 185 | 28 |
Compounds between 12 and 24 h | 73 | 11 |
Compounds greater than 24 h | 82 | 12 |
Plasma protein binding | ||
Compounds greater than 99.9% bound | 41 | 7.4 |
Compounds between 99 and 99.9% bound | 28 | 5.1 |
Compounds between 90 and 99% bound | 116 | 21 |
Compounds between 50 and 90% bound | 167 | 30 |
Compounds less than 50% bound | 202 | 36 |