Distribution of radioactivity in the gastrointestinal tract of sheep following a single 0.5-mg/kg oral dose of [3H]PHQ Values in parentheses for sheep 1 to 4 represent time of necropsy.
GI Tract | Sheep 1 (24 h) | Sheep 2 (48 h) | Sheep 3 (72 h) | Sheep 4 (96 h) | |
|---|---|---|---|---|---|
| % of administered dose | |||||
| Rumen | 28 | 1.4 | 1.4 | 0.14 | |
| Reticulum | 0.4 | 0.24 | 0.02 | 0.01 | |
| Omasum | 0.6 | 0.14 | 0.08 | 0.01 | |
| Abomasum | 1.5 | 0.22 | 0.16 | 0.03 | |
| Duodenum | 0.5 | 0.10 | 0.04 | 0.01 | |
| Jejunum | 2.1 | 0.14 | 0.10 | 0.01 | |
| Ileum | 1.3 | 0.39 | 0.29 | 0.03 | |
| Cecum | 1.9 | 1.0 | 0.31 | 0.07 | |
| Large intestine | 5.7 | 1.7 | 0.85 | 0.12 | |
| Colon | 9.9 | 1.6 | 0.79 | 0.10 | |
| Total | 52 | 6.8 | 4.0 | 0.52 | |