UGT activities in liver microsomes from the six mouse strains
Data represent the mean of duplicate determinations. The concentrations of estradiol, 4-MU, 4-NP, propofol, MPA, and morphine were 20, 100, 300, 60, 200, and 200 μM, respectively.
Strain | UGT Activities | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Estradiol | 4-MU | 4-NP | Propofol | MPA | Morphine | ||||||
| nmol/min/mg protein | |||||||||||
| C57BL/6J | 0.89 | 147 | 46 | 1.7 | 17 | 8.4 | |||||
| BALB/c | 0.77 | 199 | 71 | 1.2 | 14 | 8.5 | |||||
| C3H/HeJ | 0.79 | 169 | 62 | 1.7 | 17 | 8.4 | |||||
| DBA/2 | 0.82 | 133 | 56 | 3.5 | 28 | 8.2 | |||||
| ddY | 0.80 | 160 | 63 | 3.5 | 25 | 8.3 | |||||
| ICR | 0.71 | 136 | 65 | 3.3 | 26 | 8.6 | |||||