Mean percentage dose excreted in bile from rats after oral administration of [14C]LAS
Hours Postdose | 14C Excretion | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Male 1 | Male 2 | Mean Males | Female 1 | Female 2 | Mean Females | ||||||
| % | |||||||||||
| 0-24 | 80.3 | 79.5 | 79.9 | 48.8 | 81.5 | 65.2 | |||||
| 24-48 | 10.5 | 3.48 | 7.0 | 23.8 | 4.02 | 13.9 | |||||
| 0-48 | 90.8 | 83.0 | 86.9 | 72.6 | 85.5 | 79.1 | |||||