Mean percentage of biliary metabolites of LAS in rats after oral administration of [14C]LAS
The relative abundance of metabolites is based on the amount of radioactivity excreted in bile.
Metabolite No. | Retention Time | Percentage of Excreted Radioactivity | ||||
|---|---|---|---|---|---|---|
| Male | Female | Mean | ||||
| min | ||||||
| M2 | 19.8 | 1.37 | 1.64 | 1.51 | ||
| M3 | 21.1 | 8.18 | 5.25 | 6.72 | ||
| M4 | 22.3 | 1.74 | 0.81 | 1.28 | ||
| M5 | 23.5 | 3.92 | 2.4 | 3.16 | ||
| M10 | 24.5 | N.D. | 3.55 | 1.78 | ||
| M6 | 27.7 | 20.4 | 16.2 | 18.3 | ||
| M7 | 29.5 | 56.7 | 53.4 | 55.0 | ||
| M11 | 31.6 | 2.32 | 10.2 | 6.27 | ||
| M9 | 33.1 | 1.83 | 2.22 | 2.03 | ||