Metabolite No. | Rats | Monkeys | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Male | Female | Mean | Male | Female | Mean | |||||
M3 | 2.75 | 2.34 | 2.55 | N.D. | N.D. | N.D. | ||||
M5 | 9.14 | 7.36 | 8.25 | 14.4 | 5.10 | 9.75 | ||||
M6 | 1.52 | 2.24 | 1.88 | N.D. | N.D. | N.D. | ||||
M7 | 26.5 | 31.6 | 29.0 | 20.2 | 35.9 | 28.1 | ||||
M10 | N.D. | N.D. | N.D. | 15.3 | 8.70 | 12.0 | ||||
M11 | NA | 3.59 | 1.80 | 6.20 | 6.69 | 6.45 | ||||
M8 | 16.0 | 4.98 | 10.5 | N.D. | N.D. | N.D. | ||||
M9 | NA | 2.81 | 1.41 | N.D. | N.D. | N.D. | ||||
M13 | 2.94 | 3.46 | 3.20 | N.D. | N.D. | N.D. | ||||
M15 | 2.49 | 3.31 | 2.90 | 3.30 | 4.88 | 4.09 | ||||
LAS | 23.4 | 21.6 | 22.5 | 20.7 | 18.3 | 19.5 | ||||
M17 | 1.8 | 6.4 | 4.1 | 7.50 | 7.80 | 7.65 |
N.D., not detected