Representative retention times and percent activity of casopitant and its metabolites in pooled brain homogenate extract following i.p. dosing with [14C]casopitant at 6 mg/kg (at 120 min postdose, brain extracts from ferrets were subjected to HPLC analysis)
Peak | Retention Time | Percent Activity |
|---|---|---|
| min | ||
| M1 | 28.2 | 19.25 |
| Casopitant | 30.5 | 76.13 |
| M2 | 41.9 | 3.03 |