Binding affinities of casopitant and its metabolites in ferret brain cortical NK-1 receptor binding assays
Values presented are the mean ± S.D. (n = 8).
Compound | Ki ± S.D., Ferret Brain Cortical NK-1 |
|---|---|
| pM | |
| Casopitant | 163 ± 39 |
| M1 | 464 ± 132 |
| M2 | 108 ± 31 |