TABLE 4

Summary for time course of metabolite conjugation data

Substrate	Human Hepatocytes					NeoHep Cells
Substrate		R²	Plateau	Half-Life	R²	Plateau	Half-Life
		nmol substrate/min/mg protein	min		nmol substrate/min/mg protein	min
AHMC	0.7506	13.47 ± 0.18	8.17	0.6584	12.32 ± 0.36	16.16
CHC	0.8303	19.73 ± 0.61	7.20	0.7921	31.21 ± 1.33	13.34
HC	0.6853	2.39 ± 0.28	12.75	0.7952	7.66 ± 0.25	16.51
HFC	0.8575	13.54 ± 1.00	18.41	0.8057	38.15 ± 1.56	28.83
Fluorescein	0.7546	8.79 ± 0.41	4.61	0.6606	10.45 ± 0.58	6.23
Resorufin	0.9026	14.13 ± 0.54	7.90	0.6246	34.19 ± 1.07	17.74
MCB	0.8868	45.93 ± 7.34	214.69	0.8630	49.10 ± 5.08	264.20