Pharmacokinetic parameters of MDMA and its metabolites in plasma of rats given a single oral dose of 20 mg/kg MDMA
Values represent the mean ± S.D. (n = 24).
| Analyte | Cmax | AUC | Tmax | t1/2 |
|---|---|---|---|---|
| ng/ml | ng/ml · h | h | ||
| MDMA | 652 ± 368.7 | 4469 ± 1694.2 | 2.5 ± 1.7 | 5.8 ± 3.5 |
| MDA | 361 ± 174.1 | 3926 ± 1348.1 | 5.7 ± 2.0 | N.D. |
| HHMA | 170 ± 46.9 | 2383 ± 897.8 | 7.2 ± 2.4 | N.D. |
| HMMA | 201 ± 67.6 | 2409 ± 846.2 | 7.7 ± 2.1 | N.D. |
N.D., not determined.