TABLE 1

Dose recovered after a single intravenous,^a single oral,^a or repeated oral^b administration of [¹⁴C]BmPy-Cl to male F-344 rats n = 4/dose group.

	Dose Recovered
	1 Dose (5 mg/kg i.v.)		1 Dose (0.5 mg/kg p.o.)		1 Dose (5 mg/kg p.o.)		1 Dose (50 mg/kg p.o.)		5 Doses (5 mg/kg p.o.)
	Mean	S.D.	Mean	S.D.	Mean	S.D.	Mean	S.D.	Mean	S.D.
	%
Feces	8.4	1.3	64.8	6.8	68.6	4.3	51.0	6.2	69.4	3.4
Urine	86	12.5	38.0	8.6	28.6	1.6	37.2	10.0	22.3	1.4
Tissues	0.1	0.1	N.D.	N.D.	N.D.	N.D.	0.3	0.6	0.9	0.3
Total recovery	92.2	11.4	102.8	7.6	97.2	5.2	88.5	10.8	92.7	4.4

N.D., not determined.
↵a Studies were terminated 72 h after administration.
b Studies were terminated 24 h after final administration.