TABLE 2

Dose recovered in 96 h after dermal application of [¹⁴C]BmPy-Cl to male F-344 rats (5 mg/kg)

DMF-H₂O: 63/37, v/v; EtOH-H₂O: 63/37, v/v.

	DMF-H₂O (n = 3)		EtOH-H₂O (n = 3)		H₂O (n = 5)
	Mean	S.D.	Mean	S.D.	Mean	S.D.
Feces	4.1	1.8	3.4	1.9	5.1	4.3
Urine	19.1	3.4	2.5	0.7	9.6	3.6
Tissues	0.2	0.2	0.4	0.3	0.2	0.2
Skin
Absorbed^a	11.0	7.5	7.1	1.9	7.4	4.3
Unabsorbed^b	55.5	15.7	80.7	2.4	72.5	8.3
Total recovery in tissues	89.9	5.3	94.2	1.7	91.8	11.0

↵a Nonrecoverable ¹⁴C radioactivity present in skin at site of application.
↵b ¹⁴C radioactivity recovered by washing and tape-stripping.