TABLE 3

Quantification of the expression of five SULT isoforms in human tissue cytosols

Data are means ± S.D. for quantification of SULT expression in n tissue samples. Measurements were carried out in triplicate on each sample of cytosol. The range of values obtained with the panel of tissues is given in italics.

TissueSULT Expression
SULT1A1SULT1A3SULT1B1SULT1E1SULT2A1Total
ng/mg cytosol protein ng/mg cytosol protein ng/mg cytosol protein ng/mg cytosol protein ng/mg cytosol protein ng/mg cytosol protein
Liver (n = 28)3200 ± 1100BLQ840 ± 230340 ± 1601600 ± 4205960 ± 1400
Range 420–4900 390–1600 50–660 680–2500 2300–7900
Intestine (n = 6)1300 ± 6502000 ± 11002400 ± 1300490 ± 470390 ± 1307800 ± 4600
Range 330–2200 770–3300 440–4000 250–510 50–1300 1900–15,900
Kidney (n = 3)170 ± 90120 ± 70130 ± 110BLQ5 ± 10430 ± 270
Range 100–270 70–200 60–260 BLQ-20 240–730
Lung (n = 4)60 ± 5060 ± 8040 ± 20110 ± 11030 ± 20290 ± 130
Range BLQ-120 5–170 10–50 BLQ-260 4–50 100–370
  • BLQ, below limit of quantification.