TABLE 1

Unbound fractions of the five inhibitors in human plasma, liver microsomes, and hepatocytes

Drug	f_{u, p} (Plasma)	f_{u, mics} (HLM)	f_{u, hept} (Hepatocytes)
Drug	f_{u, p} (Plasma)	f_{u, mics} (HLM)	No Treatment	Alamethicin	ABT
CLA	0.175	0.324	0.806	0.980	0.750
DIL	0.212	0.820	0.709	0.890	0.788
ERY	0.326	0.870	0.465	0.936	0.918
VER	0.069	0.587	0.883	0.936	0.877
TAO	0.015	0.154	0.567	0.715	0.692