TABLE 3

Blood glucose levels after a single oral dose of 0.25 mg repaglinide in nine healthy volunteers after pretreatment with 600 mg of gemfibrozil twice daily, when repaglinide was administered 1, 24, 48, or 96 h after the last gemfibrozil dose

Values are mean ± S.D.

Variable	Control	Time from the Last Gemfibrozil Dose
Variable	Control	1 h	24 h	48 h	96 h
Baseline concentration (mmol/l)	5.3 ± 0.5	5.3 ± 0.5	5.3 ± 0.5	5.3 ± 0.4	5.3 ± 0.4
Minimum concentration (mmol/l)	3.2 ± 0.6	2.6 ± 0.4^*	2.9 ± 0.5	3.3 ± 0.5^†,^‡	3.4 ± 0.5^††,^‡
Mean concentration from 0 to 3 h (mmol/l)	4.5 ± 0.4	4.1 ± 0.2^*	4.3 ± 0.3	4.8 ± 0.6^††,^‡	4.5 ± 0.3^†
Mean concentration from 0 to 9 h (mmol/l)	4.6 ± 0.3	4.1 ± 0.2^*	4.5 ± 0.3^†	4.8 ± 0.4^††	4.7 ± 0.3^†††

↵* P < 0.05 vs. control.
↵† P < 0.05 vs. 1 h; †† P < 0.005 vs. 1 h; ††† P < 0.001 vs. 1 h.
↵† P < 0.05 vs. 24 h.