IC50 and Ki values of four lignans in SLE on rat hepatic microsomal MDZ 4-hydroxylation activity (n = 3)
| Components | IC50a | Ki |
|---|---|---|
| μM | μM | |
| Schizandrol A | 70 ± 10 | 45 |
| Deoxyschizandrin | 12.5 ± 2.5 | 4.8 |
| γ-Schizandrin | 6.25 ± 1.5 | 5 |
| Gomisin C | 0.30 ± 0.05 | 0.06 |
↵a Values are the mean ± S.D. of three determinations (i.e., three rat hepatic microsomal preparations).