Total | Genotype (Frequency) | Activity, Diazepam p-Hydroxylation | |||||
---|---|---|---|---|---|---|---|
Wild Homozygote | Heterozygote | Mutant Homozygote | |||||
pmol/min/mg protein | |||||||
SD | 9 | 9 (100%) | 0 | 0 | 171.9 ± 3.0* | ||
BN | 9 | 9 (100%) | 0 | 0 | 156.4 ± 8.3* | ||
DA | 8 | 0 | 0 | 8 (100%) | 0.4 ± 0.0 | ||
PM-W | 33 | 0 | 0 | 33 (100%) | 0.5 ± 0.0 | ||
EM-W | 8 | 0 | 8 (100%) | 0 | 94.6 ± 16.0* |
↵* Significant difference from PM-W rats (P < 0.01).