Differential expression of P450 genes in workers with chronic benzene poisoning workers and matched control subjects
Numbers in parentheses refer to numbers of patients with benzene poisoning.
GenBank | GeneTag | Gene Function | Up-Regulation | Down-Regulation |
|---|---|---|---|---|
| A1927693 | CYP4F3A | CYP450, subfamily IVF, polypeptide 3 (leukotriene B4 ω hydroxylase) | 7/7 | |
| AA418907 | CYP1A1 | CYP450, subfamily I (aromatic compound-inducible), polypeptide 1 | 4/7 (2, 5, 6, 7) | |
| N66957 | CYP27A1 | CYP450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 | 1/7 (1) | 3/7 (2, 5, 6) |
| AA448157 | CYP1B1 | CYP450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) | 2/7 (4, 6) | |
| T68287 | CYP2B6 | CYP450, subfamily IIB (phenobarbital-inducible), polypeptide 6 | 1/7 (1) | |
| AA477781 |
CYP51
| CYP450, 51 (lanosterol 14-α-demethylase) |
| 1/7 (1) |