Hepatic CBR1 expression in samples stratified by ethnicity and AIM-determined geographical ancestry
Number of samples is indicated in parentheses.
Ethnicity Black | White | AIM-Determined Geographical Ancestry Sub-Saharan African | European | p (Black vs. Sub-Saharan African) | p (White vs. European) | |
|---|---|---|---|---|---|---|
| CBR1 mRNA (relative -fold) | 4.8 ± 4.3 (23) | 3.6 ± 3.6 (30) | 4.8 ± 4.3 (23) | 3.9 ± 3.8 (33) | 1.000 | 0.728 |
| CBR1 protein (nmol/g cytosolic protein) | 8.0 ± 3.4 (28) | 9.0 ± 4.6 (28) | 8.1 ± 3.5 (25) | 9.9 ± 4.8 (20) | 0.897 | 0.522 |
| Maximal CBR activity (nmol doxol/min · mg) | 4.2 ± 2.3 (20) | 3.9 ± 2.1 (40) | 4.2 ± 2.3 (20) | 3.9 ± 2.2 (29) | 1.000 | 0.991 |