Cytotoxicity of pentamidine and furamidine in CHO-hOCT2 cells and the mock CHO cells
Drug | hOCT2 IC50 | Mock IC50 | -Fold Changea |
|---|---|---|---|
| μM | μM | ||
| Pentamidine | 152.7 ± 17.3 | 161.8 ± 14.4 | 1.06 |
| Furamidine | 14.7 ± 1.5 | 13.8 ± 1.6 | 0.94 |
↵ a -Fold increase in the sensitivity of the transfected cells to pentamidine and furamidine cytotoxicity compared with the mock cells incubated under identical conditions.