Cytotoxicity of pentamidine and furamidine in CHO-hOCT3 cells and the mock CHO cells
Drug | hOCT3 IC50 | Mock IC50 | -Fold Changea |
|---|---|---|---|
| μM | μM | ||
| Pentamidine | 178.3 ± 16.3 | 161.8 ± 14.4 | 0.91 |
| Furamidine | 16.1 ± 2.1 | 13.8 ± 1.6 | 0.86 |
↵ a -Fold increase in the sensitivity of the transfected cells to pentamidine and furamidine cytotoxicity compared with the mock cells incubated under identical conditions.