[14C]YM155 Concentration | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
10 ng/ml (0.028 μM) | 100 ng/ml (0.28 μM) | 1000 ng/ml (2.8 μM) | 5 ng/ml (0.014 μM) | 50 ng/ml (0.14 μM) | 500 ng/ml (1.4 μM) | ||||||
Unbound fraction, % | 77.62 (1.38) | 79.14 (1.05) | 81.40 (1.32) | ||||||||
Blood-to-plasma ratio | 0.59 (0.02) | 0.59 (0.01) | 0.58 (0.01) | ||||||||
Blood cell-to-plasma ratio |
|
|
| 0.17 (0.004) | 0.18 (0.03) | 0.15 (0.02) |