LC/MS/MS characterizations of BMS-275183 and prominent metabolites
Compound | HPLC Rt | [M + NH4]+ | Major Fragment Ions |
|---|---|---|---|
| min | |||
| Parent (BMS-275183) | 57.5 | 863 | 585, 567, 525, 449, 387, 327, 287, 177, 151, 206, 162 |
| M0 | 17.24 | 277 | 204, 160, 143 |
| M13 | 19.7 | 620 | 525, 467, 449, 405, 345, 327, 309, 105 |
| M20 | 42.5 | 877 | 585, 525, 409, 387, 345, 309 |
| M21 | 44.3 | 875 | 585, 543, 525, 387, 327 |
| M22 | 43.8 | 893 | 585, 525, 387 |
| M23 | 46.8 | 879 | 567, 525, 327, 278, 206 |
| M20B | 62.4 | 877 | 585, 525, 449, 327, 309 |