Unbound fractions in brain and blood
Data represent mean ± S.D. from n = 3 to 5 experiments.
Compound | fu,brain | fu,blood |
|---|---|---|
| Chlorpromazine | 0.002 ± 0.0004 | 0.016 ± 0.002 |
| Clozapine | 0.011 ± 0.001 | 0.066 ± 0.010 |
| Haloperidol | 0.011 ± 0.0007 | 0.104 ± 0.039 |
| Quetiapine | 0.025 ± 0.002 | 0.080 ± 0.003 |
| Risperidone | 0.099 ± 0.003 | 0.144 ± 0.018 |
| Ziprasidone | 0.001 ± 0.0001 | 0.041 ± 0.003 |