TABLE 2

Summary of ratio of efflux ratios for compounds tested in Transwell assays


Compounds

RRMDR1

RRMdr1a

RRBCRP

RRBcrp
Flavopiridol 3.1 3.0 6.0 8.2
Imatinib 4.7 4.0 2.4 2.3
PF-407288 1.1 1.1 6.9 3.7
Prazosin
2.1
2.3
4.3
8.5
  • RRMDR1, ERMDR1/ERMDCK; RRMdr1a, ERMdr1a/ERMDCK; RRBCRP, ERBCRP/ERMDCK; RRBcrp, ERBcrp I/ERBcrp U.