Unbound fractions for four compounds in mouse plasma and mouse brain
Data are presented as mean ± S.D. from three independent determinations.
fu, plasma | fu, brain | |
|---|---|---|
| Flavopiridol | 0.26 ± 0.03 | 0.04 ± 0.00 |
| Imatinib | 0.09 ± 0.00 | 0.03 ± 0.01 |
| PF-407288 | 0.03 ± 0.00 | 0.07 ± 0.01 |
| Prazosin | 0.35 ± 0.03 | 0.09 ± 0.01 |