Summary of metabolites of fenofibrate in different species
Metabolites of fenofibrate in human, guinea pig, dog, rat, and rat hepatocytes were obtained from the indicated references in the text (Weil et al., 1988, 1990; Cornu-Chagnon et al., 1995).
Metabolites | Human | Monkey | Guinea Pig | Dog | Rat | ||
|---|---|---|---|---|---|---|---|
| Rat | Rat Hepatocyte | ||||||
| FA | Yes | Yes | Yes | Yes | Yes | Yes | |
| FAEG | Yes | Yes | Yes | Yes | Yes | ||
| RFA | Yes | Yes | Yes | Yes | Yes | Yes | |
| RFAEG | Yes | Yes | Yes | Yes | |||
| AR | Yes | ||||||
| Compound B | Yes | ||||||
| Compound X | Yes | Yes | |||||
| FAT | Yes | ||||||
| RFAT |
| Yes |
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