Inhibitory constants of novobiocin on OAT-mediated organic anion transport
Transporters | Uptake of Substrates | Ki | IC50 |
|---|---|---|---|
| μM | μM | ||
| hOAT1 | PAH | 14.87 ± 0.40 | 34.76 ± 0.31 |
| hOAT3 | Estrone sulfate | 4.77 ± 1.12 | 4.99 ± 0.35 |
| hOAT4 | Estrone sulfate | 90.50 ± 7.50 | 92.68 ± 0.34 |