Pharmacokinetic Parameter | [14C]Bazedoxifene | Total Radioactivity |
---|---|---|
Cmax (ng/ml or ng Eq/ml) | 3.43 ± 1.14 | 75.7 ± 26.7 |
tmax (h) | 1.2 ± 0.4 | 1.2 ± 0.4 |
Half-life (h) | 32.8 ± 15.6 | 10.2 ± 3.6 |
AUCT (ng · h/ml or ng Eq/ml)a | 54 ± 14 | 732 ± 204 |
AUC (ng · h/ml or ng Eq/ml) | 56 ± 14 | 746 ± 193 |
Cl/F (l/h/kg) | 5.2 ± 1.4 | |
V/F (l/kg) | 248 ± 134 |
|
↵ a T varied for each subject, depending on when the last measurable sample was taken.