TABLE 2

Expression of P450 genes in primary mouse hepatocytes at 42 and 90 h as percentages of the expression at 0 h

Gene Name
42 h
90 h
Cyp17a1* 2659 107
Cyp1a1 119 117
Cyp1a2* 29 7
Cyp1b1 109 104
Cyp20a1 155 213
Cyp21a1 114 108
Cyp26a1* 24 10
Cyp27a1* 66 56
Cyp2a12* 65 128
Cyp2a4/5 42 71
Cyp2b10 1546 1460
Cyp2b13 102 95
Cyp2b19 90 86
Cyp2b9 126 110
Cyp2c29* 32 13
Cyp2c37 24 1
Cyp2c37/50/54* 19 1
Cyp2c38 54 65
Cyp2c44* 27 2
Cyp2c55* 50 16
Cyp2c70* 75 39
Cyp2d10* 88 59
Cyp2d13* 40 20
Cyp2d22* 74 33
Cyp2d26* 69 56
Cyp2d9* 59 22
Cyp2e1* 56 3
Cyp2f2* 22 4
Cyp2g1* 40 37
Cyp2j5* 10 6
Cyp2j6* 99 83
Cyp2r1 103 76
Cyp2s1* 266 83
Cyp2u1 76 80
Cyp39a1* 197 421
Cyp3a11* 77 76
Cyp3a13* 203 175
Cyp3a25* 21 18
Cyp3a41* 66 65
Cyp3a44* 82 77
Cyp46a1* 83 67
Cyp4a10* 32 38
Cyp4a12* 16 1
Cyp4a14* 19 7
Cyp4b1 202 100
Cyp4f13 70 58
Cyp4f14* 19 5
Cyp4f15* 26 9
Cyp4f16* 381 341
Cyp4v3* 41 22
Cyp51 115 108
Cyp7a1 76 42
Cyp7b1* 17 12
Cyp8b1* 109 7
69
57

  • ↵* Significant (p < 0.05) in multiclass SAM.