Substituent | Putative Responsible Entity | Example |
---|---|---|
Aliphatic amine | Nitroso | Clarithromycin |
Alicyclic amine | Iminium ion | Phencyclidine |
Cyclopropylamine | Radical | Tranylcypromine |
Methylenedioxyphenyl | Carbene | Paroxetine |
Furan | α,β-Unsaturated carbonyl or epoxide | Methoxsalen |
Thiophene | S-oxide or epoxide | Tienilic Acid |
Alkenes | Cation radical | Secobarbital |
Alkynes | Ketene or oxirene | Gestodene |
2-Alkylimidazole | Imidazomethide | Furafylline |
3-Alkylindole | α,β-Unsaturated imine | Zafirlukast |
Dihaloalkane | Acylhalide | Chloramphenicol |
Hydrazine | Radical | Dihydralazine |
Aminophenol | Quinoneimine | Nefazodone |
Phenol | Quinone | Raloxifene |