Allele | Present Study | Reference Dataa: Observed Frequency (95% Confidence Interval) | ||
---|---|---|---|---|
Occurrence | Observed Frequency (95% Confidence Interval) (%) | |||
*1 | 489 | 32.32 (28.67-35.32) | 33.25 (29.88-36.63) | |
*2b | 151 | 9.89 (7.76-12.01) | 10.13 (8.13-12.25) | |
*2c | 2 | 0.99 (0.28-0.16) | N.D. | |
*5 | 85 | 5.61 (3.97-7.24) | 6.13 (4.50-7.88) | |
*10 | 691 | 45.58 (42.03-49.12) | 45.00 (41.63-48.25) | |
*14 | 5 | 0.33 (0.00-0.73) | 0.50 (0.13-1.00) | |
*18 | 4 | 0.26 (0.00-0.62 | N.D. | |
*21 | 5 | 0.33 (0.00-0.73) | 0.25 (0.00-0.63) | |
*41 | 34 | 2.24 (1.34-3.53) | 1.88 (0.00-0.88) | |
*49 | 21 | 1.39 (0.55-2.22) | N.D. | |
*52 | 5 | 0.33 (0.00-0.73) | N.D. | |
*60 | 1 | 0.07 (0.00-0.26) | N.D. | |
*1xN | 2 | 0.07 (0.00-0.26) | 0.13 (0.00-0.38) | |
*2xN | 15 | 0.99 (0.28-0.16) | 0.50 (0.13-1.00) | |
*10xN | 6 | 0.40 (0.00-0.84) | 0.50 (0.13-1.00) |
N.D., not detected.
↵ a CYP2D6 polymorphisms in 400 subjects were described previously (Lee et al., 2006).
↵ b Alleles carrying -1584G.
↵ c Alleles carrying -1584C.