Ancestry of Individuals | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNAa | Encoded Protein | Africanb | Hispanicc | Africand | Hispanicd | Europeand | Asiand | ||||||
dbSNP Number | |||||||||||||
rs2020862 | C>T | S195L | 0.51 | 0.37 | 0.46 | 0.55 | 0.30 | 0.52 | |||||
rs2020865 | T>G | N413K | 0.27 | 0.11 | 0.24 | 0.02 | 0.02 | 0.00 | |||||
rs6661174 | C>T | Q472X | 0.11 | 0.05 | 0.20 | 0.06 | 0.00 | 0.00 | |||||
Individuals | 50 | 153-632 | 26 | 20 | 20 | 24 | |||||||
Alleles |
|
| 100 | 306-1264 | 52 | 40 | 40 | 48 |
↵ a The ancestral allele is shown first and is followed by the alternative nucleotide. The nucleotide present in the minor allele is underlined and bolded. Note that for Q472X the minor “C” allele is the ancestral allele.
↵ c Frequency for occurrence of the allele encoding Gln472 (FMO2*1) was made from 632 Hispanic individuals (primarily of Mexican and Puerto Rican ancestry) (Krueger et al., 2004). Estimates for the remaining two alleles (Krueger et al., 2005) were from a subset of the first population, 29 individuals with at least one FMO2*1 allele and 124 individuals homozygous for FMO2*2.
↵ d Frequency data from the National Institute of Environmental Health Sciences SNPs database (http://egp.gs.washington.edu).