TABLE 1

LC retention times, accurate masses, elemental compositions, and postulated molecular structures of nomifensine monooxygenated metabolites identified in human liver microsomes

Compound	R_t	Elemental Composition	Measured Mass	Calculated Mass	Mass Error	ΔM
	min		Da	Da	ppm
Nomifensine	11.59	[C₁₆H₁₉N₂]⁺	239.1546	239.1543	1.4
H1	2.70	[C₁₆H₁₉N₂O]⁺	255.1494	255.1492	0.82	+16
H2	7.91	[C₁₆H₁₉N₂O]⁺	255.1492	255.1492	0.04	+16
H4	9.32	[C₁₆H₁₉N₂O]⁺	255.1494	255.1492	0.82	+16
H6	11.42	[C₁₆H₁₉N₂O]⁺	255.1495	255.1492	1.2	+16
H7	12.57	[C₁₆H₁₉N₂O]⁺	255.1492	255.1492	0.04	+16
H8	12.99	[C₁₆H₁₉N₂O]⁺	255.1495	255.1492	1.2	+16