TABLE 1
IC
50
and EC
50
values of roscovitine transport
ABC Transporters
Assays
EC
50
IC
50
μ
M
MDR1
ATPase assay
4.2
Vesicular transport assay
35.5
Calcein AM assay
11.5
BCRP
ATPase assay
63
Hoechst assay
38