TABLE 2

Pharmacokinetic parameters for [125I]T4 after the administration of [125I]T4 to the CB126-pretreated mice

The data shown were calculated from the data in Fig. 8. The values shown are expressed as the mean ± S.E. for five to eight mice.

C57BL/6DBA/2
ControlCB126ControlCB126
Mean total body clearance (ml/min)0.015 ± 0.0010.025 ± 0.002*0.012 ± 0.00030.012 ± 0.001
Distribution volume (ml)2.90 ± 0.173.06 ± 0.122.50 ± 0.082.72 ± 0.06
  • * P < 0.05, significantly different from each control.