Tamoxifen-Metabolizing Enzymes Expressed in Glandular and Surface Epithelium | Number of Positive Individualsa | Number of Positive Individuals in Proliferative Phase | Number of Positive Individuals in Secretory Phase |
---|---|---|---|
CYP1B1 | 8/10 | 4 | 4 |
CYP2A6 | 4/11 | 2 | 2 |
CYP2B6 | 8/11 | 4 | 4 |
CYP2C8/9/19 | 5/13 | 4 | 1 |
CYP2D6 | 6/14 | 5 | 1 |
SULT2A1 | 2/8 | 1 | 1 |
↵a Individuals who showed a significant expression of drug-metabolizing enzymes in glandular epithelium compared to other cell types were considered as positive.