Enzymatic parameters of ECB glucuronidation by human liver microsomes and recombinant human UGT isoforms
| Source of UGT | Km | Vmax | Clint |
|---|---|---|---|
| μM | nmol/min · mg protein | ml/min · mg protein | |
| Human liver microsomes | 206.0 ± 45.9 | 60.0 ± 3.5 | 0.291 |
| Recombinant human UGT1A6 | 117.3 ± 21.3 | 19.9 ± 0.7 | 0.170 |
| Recombinant human UGT1A9 | 435.8 ± 144.0 | 35.8 ± 9.1 | 0.082 |