Sila-haloperidol and metabolites–fragmentation ions
| Metabolite | tR (min) | [M+H]+m/z | Major Product Ions m/z |
|---|---|---|---|
| N-Dealk | 1.22 | 228.0608 | 190.0103, 192.0023, 172.0007, 173.9888 |
| Ring-opened1+OH | 1.28 | 380.0875 | 380.0869, 382.0974, 188.9782, 190.9616, 164.0897 |
| +OH+Gluc | 1.52 | 564.1508 | 584.1495, 586.1488, 408.1197, 410.1167, 165.0723, 164.0868 |
| Ring-opened1 | 1.74 | 364.0931 | 364.0929, 366.0962, 172.9830, 174.9805, 164.0888 |
| +OH+Sulfate | 1.82 | 488.0763 | 408.1190, 165.0749, 164.0860, 123.0249 |
| OH | 1.90 | 408.1191 | 408.1189, 410.1153, 165.0714, 164.0877, 123.0277 |
| Ring-opened2 | 1.94 | 382.1031 | 382.0978, 172.9830, 174.9806, 165.0711, 164.0943, 123.0249 |
| Red | 2.01 | 394.1405 | 394.1395, 396.1375, 376.1292, 378.1279, 320.0648, 322.0673, 172.9824, 174.9797, 109.0477 |
| Sila-haloperidol | 2.18 | 392.1238 | 392.1243, 394.1137, 165.0698, 164.0886, 123.0283 |