TABLE 1

LC retention times (R_t), accurate masses, chemical formulas, and postulated molecular structures of the nomifensine GSH conjugates identified in liver microsomes (see Fig. 2)

Compound	R_t	Chemical Formula	Measured Mass	Calculated Mass	Mass Error	ΔM
	min		Da	Da	ppm
Nomifensine	11.42	[C₁₆H₁₉N₂]⁺	239.1546	239.1543	1.4
M1	8.52	[C₂₆H₃₅N₅O₇S]²⁺	280.6127	280.6126	1.4	+321
M2	8.35	[C₂₆H₃₅N₅O₇S]²⁺	280.6127	280.6126	1.4	+321
M3	8.13	[C₂₆H₃₅N₅O₇S]²⁺	280.6126	280.6126	1.0	+321
M4	7.72	[C₂₆H₃₅N₅O₇S]²⁺	280.6126	280.6126	1.0	+321
M5	6.39	[C₂₆H₃₅N₅O₇S]²⁺	280.6128	280.6126	1.7	+321
M6	6.00	[C₂₆H₃₅N₅O₇S]²⁺	280.6126	280.6126	1.0	+321
M7	5.60	[C₂₆H₃₅N₅O₇S]²⁺	280.6127	280.6126	1.4	+321
M8	5.27	[C₂₆H₃₅N₅O₇S]²⁺	280.6128	280.6126	1.7	+321
M9	4.60	[C₂₆H₃₅N₅O₇S]²⁺	280.6128	280.6126	1.7	+321