TABLE 1

Excretion of total radioactivity following single intravenous and oral administrations of [¹⁴C]procyanidin B2 in male rats

[¹⁴C]Procyanidin B2 was administered to rats as either a single intravenous dose (group I received 21 mg/kg) or oral dose (group II received 21 mg/kg; group III received 10.5 mg/kg). Data represent total ¹⁴C radioactivity, i.e., the parent compound and/or metabolites. Results are mean ± S.D. for nine animals.

Time after Administration	Excretion in Urine	Excretion in Feces	Sum
h	% of dose	% of dose	% of dose
Group I
0–24	68.7	24.6	93.3
24–48	4.3	2.9	7.2
48–72	1.8	0.2	2
72–96	0.8	0.2	1
Total (% of dose)	75.6 ± 5.4	27.9 ± 5.6	103.5 ± 5.5
Group II
0–24	58.3	39.6	97.9
24–48	2.7	0.1	2.8
48–72	1.4	0.1	1.5
72–96	0.5	0.05	0.55
Total (% of dose)	62.9 ± 5.8	39.9 ± 9.2	102.8 ± 7.5
Group III
0–24	57.8	40.8	98.6
24–48	3	0.2	3.2
48–72	0.8	0.05	0.85
72–96	0.6	0.05	0.65
Total (% of dose)	62.2 ± 7.6	41.1 ± 9.4	103.3 ± 8.5