Marker Substrate Activity | 3-O-CP UGT Activity | 1-O-CP UGT Activity | ||||||
---|---|---|---|---|---|---|---|---|
CP = 30 μM | CP = 3000 μM | CP = 30 μM | CP = 3000 μM | |||||
rs | P | rs | P | rs | P | rs | P | |
AZT glucuronidation | 0.85 | 0.000a | 0.65 | 0.038a | 0.83 | 0.000a | 0.79 | 0.0038a |
Propofol glucuronidation | 0.44 | 0.180 | 0.71 | 0.018a | 0.16 | 0.63 | 0.31 | 0.36 |
Serotonin glucuronidation | −0.01 | 0.97 | 0.31 | 0.36 | −0.10 | 0.76 | −0.079 | 0.81 |
rs, Spearman rank order correlation coefficient.
↵a The correlations were considered statistically significant when the rs value was greater than or equal to 0.50 and the P value was less than 0.05.