TABLE 2

Candidate ARE enhancers in the AKR1B13 and AKR1D2 promoter regions

The 10-kb DNA sequence upstream of the AKR1B13 and AKR1D2 translational start sites were searched for candidate AREs using the consensus sequence 5′-TGA(C/G)NNNGC-3′. Nucleotide location of the first consensus matched base (T) relative to the start codon is presented.

GeneLocationSequenceStrand
AKR1B13−104G TGAGCAAGC A
−3597A TGATTCAGC A
−4957A TGAGAAAGC A
−9044C TGACAATGC A
AKR1D2−2282T TGAGGAGGC C
−4088T TGACTCAGC C+
−4709C TGACATTGC C+
−5494T TGAGGCAGC T+
−5856C TGATCAAGC T+
−6232A TGATGGAGC A
−9050A TGAGGATGC T+
−9168G TGATTCAGC C+