TABLE 5

Overlap with CYP3A4 metabolism

Compound2J23A42D62C82C191A21A12A62B6FMOReferences
TerfenadineXXRodrigues et al., 1995
AstemizoleXXXMatsumoto and Yamazoe, 2001; Matsumoto et al., 2002
EbastineXXHashizume et al., 2002; Liu et al., 2006
AmiodaroneXXXXxXFabre et al., 1993; Ohyama et al., 2000
AlbendazoleXXXRawden et al., 2000
DanazolXXXGenerated by authors
ThioridazineXXXXXvon Bahr et al., 1991; Eap et al., 1996; Berecz et al., 2003; Wójcikowski et al., 2006
TamoxifenXXXXXXXJacolot et al., 1991; Dehal and Kupfer, 1997; Sridar et al., 2002
CyclosporineXXKronbach et al., 1988; Dai et al., 2004
NabumetoneXXXGenerated by authors
MesoridazineXXXEap et al., 1996; Salih et al., 2007

  • FMO, flavin-containing monooxygenase.