Relative contribution of [14C]anacetrapib and metabolites to the radioactivity in human plasma and feces after an oral dose of 150 mg/165 μCi of [14C]anacetrapib
| Compounds | Plasma | Feces | |||
|---|---|---|---|---|---|
| 3 h | 8 h | 20 h | 36 h | ||
| % radioactivity | |||||
| Anacetrapib | 94 | 91 | 79 | 86 | 91 |
| M1 | 1 | 0 | 0 | 0 | 1 |
| M2 | 4 | 8 | 14 | 11 | 4 |
| M3 | 1 | 1 | 7 | 3 | 3 |