Percentage of dose recovered after administration of a single oral dose of [14C]BMS-690514 to rats and dogs
| Species | Dose | Collection Interval | Percentage of Dose Recovered | |||||
|---|---|---|---|---|---|---|---|---|
| Urine | Feces | Bile | Cage Debris/Wash | Carcass | Total | |||
| mg/kg | h | |||||||
| Rat | 15 | 0–168 | 18.40 ± 1.12 | 71.19 ± 5.55 | N.A. | 5.44 ± 6.09 | 0.40 ± 0.07 | 95.43 ± 2.89 |
| BDC Rat | 15 | 0–24 | 17.13 ± 3.89 | 5.77 ± 2.93 | 83.37 ± 6.08 | 1.01 ± 0.46 | N.A. | 107.3 ± 1.73 |
| Dog | 10 | 0–168 | 20.12 ± 3.76 | 60.78 ± 11.82 | N.A. | 8.67 ± 7.45 | N.A. | 89.57 ± 4.67 |
N.A., not applicable.