TABLE 6

In vitro parameters and predicted F_g of cyclosporine and felodipine

	P_app^{^a}	CL_m,index	Predicted F_g^{^b}
	P_app^{^a}	CL_m,index		α
	(×10⁻⁶ cm/s)
			0.43	0.64	1.13
Cyclosporine	15.9	0.30	0.886	0.839	0.747
Felodipine	9.9	2.80	0.454	0.358	0.240

↵a Estimated from PAMPA.
↵b Predicted from the simplified F_g model.