Metabolite | Rat | Dog | Monkey | Human |
---|---|---|---|---|
M0 | 100 | 100 | 100 | 100 |
M1 | 2.28 | 1.77 | — | 4.13 |
M2-1 | 1.40 | 11.9 | — | 5.65 |
M2-7 | 1.06 | 7.44 | — | 0.626 |
M2-9 | 1.79 | 6.05 | — | 7.16 |
M3 | 276 | 481 | 60.0 | 33.5 |
M4 | 79.6 | 63.4 | 2.68 | 1.20 |
M5 | 28.2 | 9.47 | 2.61 | 0.519 |
M8-2 | 2.50 | — | — | — |
M8-3 | 4.59 | — | — | 0.479 |
M8-4 | 3.29 | 4.33 | — | — |
M10 | 114 | — | 0.958 | 1.54 |
M16-2 | — | — | — | 2.63 |
M17 | 6.16 | — | — | — |
M0′ | — | — | 3.14 | — |
—, Not detected.